Materials and Methods: This is a prospective cohort study of 15 eyes of 15 patients with various types of open-angle glaucoma that were treated with single session of PSLT. Patients demographic characteristics, type of glaucoma, and necessity of antiglaucoma treatments were evaluated. After full ophthalmological examination, IVCM was performed before and after PSLT. Follow-up visits were at 1 day, 1 week, 1 month.

Results: The mean age of the participants included in the study was 68.13±11.58 (56-86) years. According to glaucoma types; 53.3% of the participants were primary open-angle glaucoma, 40.0% were pseudoexfoliative glaucoma, and 6.7% were steroid induced glaucoma. There was no statistically significant difference between the SND values of pre-procedure, post-procedure 1st day, post-procedure 1st week, post-procedure 1st month. Post-procedure 1st day DCD values increased significantly compared to pre-procedure, the increase continued in the 1st week, and the difference disappeared by the 1st month. There was no significant difference in terms of both SND and DCD values before and after the procedure.

Conclusions: The increase in DND, after a single dose of PSLT, was reverted to baseline values as of the 1st month. This may be a biomarker that shows PSLT efficacy as well as the severity of the inflammatory state. Keywords : Glaucoma, Selective laser trabeculoplasty, Pattern scanning laser trabeculoplasty, In vivo confocal microscopy, Dendritic cell density