Materials and Methods: In total, 60 eyes of 30 patients with wet macular degeneration (Group 1) in one eye and dry macular degeneration (Group 2) in the other eye were compared with 50 eyes of 50 healthy people (Group 3) for CCT, endothelial cell density (CD), coeffi cient of variation (CV) and hexagonality (HEX) values. Patients who had undergone ocular surgeries or used ocular or systemic medication were excluded from the study.

Results: The ARMD group comprised 17 men and 13 women (average age,71.76±5.26 years), whereas the healthy group comprised 27 men and 23 women (average age,70.14±2.14 years); the difference between these groups was not statistically signifi cant (p=0.96 and p=0.11, respectively). Groups 1, 2 and 3 had CCT of 534.0±20.34, 528.46±24.26 and 513.04±33.47 ?m, an CD of 2312.43±740.81, 2451.40±587.42 and 2414.22±379.91 cells/mm2, a CV of 33.60%±7.08%, 34.30%±5.65% and 33.74%±4.78% and a HEX of 52.80%±9.57%, 51.96%±7.06% and 52.74%±9.16%, respectively. Regarding CCT, no statistical difference was observed between Groups 1 and 2 (p=0.34), whereas a statistical difference was observed between Groups 1 and 3 (p=0.003) and between Groups 2 and 3 (p=0.031). There were no differences among groups regarding other parameters (p>0.05).

Conclusion: While there were no differences among the CCT values of patients with wet ARMD in one eye and dry ARMD in the other eye, their CCT values were higher than those of the control group. There was no difference among other parameters. Keywords : Macular degeneration, Specular microscopy, Cornea