2Yrd. Doç. Dr., Karabük Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı Karabük - Türkiye Purpose: Evaluation of specular microscopy parameters and central corneal thickness in patients with iron defi ciency anemia (IDA).
Material and Methods: Right eye of 40 female patients who were diagnosed with IDA by our hospital?s internal medicine clinic were included in study group and 40 healthy female?s right eye were in control group. Central corneal thickness (CCT), endothelial cell density (CD), coeffi cent variation (CV) and hexagonality (HEX) values were measured with specular microscopy device.
Results: Mean age of study group was 35,70±9,09 years while control group?s was 33,47±9,30 (p = 0.295). CCT of study group was 535,45±33,72 ?m while control group?s was 535,78±24,55 ?m thus statistical difference between groups was not signifi cant (p=0,962). CD of study group was 2843,87±353,12 cell/mm2 while 2897,44±266,89cell/mm2 in the control group, thus statistics was insignifi cant (p=0.617). Of study group, CV was 31,33±4,14% and HEX was 50,75±10,47 % while these values were 28,36±3,34 % and 57,25±5,20 % in control group, representing statistical signifi cancy (p=0.001, p=0.006, respectively).
Conclusion: While CCT and CD values of iron defi ciency anemia patients were similar with healthy individuals, CV was higher and HEX was lower than healthy individuals.
Keywords : Specular microscopy, iron defi ciency, anemia