2M.D. Asistant, Sakarya University Training and Research Hospital, Eye Clinic, Sakarya/TURKEY
3M.D. Professor, Sakarya University Training and Research Hospital, Department of Internal Medicine, Sakarya/TURKEY Purpose: The ocular pulse amplitude (OPA) is the difference between systolic and diastolic intraocular pressure (IOP). The purpose of this study was to assess the relationship of OPA with systemic blood pressure and ocular biometric factors in healthy subjects.
Materials and Methods: 104 healthy subjects aged between 40-75 years were included in the study. Ocular pulse amplitude and IOP were measured by dynamic contour tonometry, and central corneal thickness (CCT), axial length (AL), anterior chamber depth (ACD), and systolic and diastolic blood pressure (SBP and DBP) measurements were performed in addition to a routine ophthalmologic examination. Associations between OPA and IOP, SBP, DBP, AL, CCT and ACD were analyzed with Pearson correlation analysis.
Results: A total of 208 eyes of 104 cases were included in the study. The mean age of the patients was 51.02 (±6.68) years with 49 (47.1%) females and 55(52.9%) males. Mean values were as follows: OPA 2.92±1.68 mmHg, AL 23.2±0.91 mm, CCT 546.6±34.8 μm, ACD 3.1±0.5 mm, SBP 134.6±25.4 mmHg and DBP 76.2±13.6 mmHg. Correlation analysis showed significant association between OPA and IOP (p=0.000). Low OPA was associated with low IOP and long AL, whereas no correlation was found between age, sex, SBP, ACD and CCT with OPA.
Conclusion: In healthy subjects, ocular pulse amplitude was significantly associated with intraocular pressure and axial length but not with age, anterior eye structures and systemic blood pressure.
Keywords : Ocular pulse amplitude, Pascal dynamic contour tonometry, systemic blood pressure